The Johnson Papers

The Johnson Papers

The Oral Microbiome and Systemic Disease: Rewriting the Mouth-Body Connection

Understanding how microbial balance in the mouth influences inflammation and systemic health

John W. Johnson, DDS's avatar
John W. Johnson, DDS
Oct 08, 2025
∙ Paid

Introduction

As a biological dentist, I’ve long believed the mouth is more than just an isolated system of teeth and gums.

Recent research now confirms what holistic providers have known for decades: the oral cavity is a gateway to the body, and the microbes that live there play a profound role in systemic wellness.

This paper offers a clinical update for professionals—where the science is headed, what it means for patients, and how dentistry can evolve to support total-body health through microbial balance.

“We are not just treating teeth—we are tending to ecosystems.”
— Dr. John Johnson, DDS

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